methyl 2-fluoro-5-nitrobenzoate
methyl 2-fluoro-5-nitrobenzoate
CAS: 2965-22-2
Molecular Formula: C8H6FNO4
methyl 2-fluoro-5-nitrobenzoate - Names and Identifiers
methyl 2-fluoro-5-nitrobenzoate - Physico-chemical Properties
| Molecular Formula | C8H6FNO4 |
| Molar Mass | 199.14 |
| Density | 1.388 |
| Melting Point | 49-51℃ |
| Boling Point | 303℃ |
| Flash Point | 137℃ |
| Vapor Presure | 0.000967mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.533 |
methyl 2-fluoro-5-nitrobenzoate - Risk and Safety
| Hazard Class | IRRITANT |
methyl 2-fluoro-5-nitrobenzoate - Introduction
methyl 2-fluoro-5-nitrobenzoate is an organic compound with the chemical formula C8H6FNO4. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless crystal
-Solubility: Soluble in organic solvents such as ethanol, dichloromethane and ether
-Melting point: about 72-75 degrees Celsius
-Boiling point: About 248 degrees Celsius
-Density: about 1.44g/cm³
Use:
- methyl 2-fluororo-5-nitrobenzoate is a commonly used organic synthesis intermediate that can be used to synthesize other organic compounds.
-It has a wide range of applications in the fields of drugs, pesticides and dyes.
Method:
The preparation method of methyl 2-fluororo-5-nitrobenzoate can be carried out by the following steps:
1. First, methyl 2-fluorobenzoate is reacted with nitric acid to generate 2-fluoro-5-nitrobenzoic acid.
2. Then, the obtained 2-fluoro-5-nitrobenzoic acid is reacted with methanol in the presence of an acid catalyst to generate methyl 2-fluororo-5-nitrobenzoate.
Safety Information:
- methyl 2-fluororo-5-nitrobenzoate is an organic compound, and you need to pay attention to safety measures during operation.
-It may be irritating to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment such as gloves, safety glasses and masks when handling.
-During storage and handling, it is necessary to avoid contact with strong oxidants such as oxidants to avoid the risk of fire or explosion.
-Read and follow the relevant safety guidelines and operating procedures before use.
Nature:
-Appearance: colorless crystal
-Solubility: Soluble in organic solvents such as ethanol, dichloromethane and ether
-Melting point: about 72-75 degrees Celsius
-Boiling point: About 248 degrees Celsius
-Density: about 1.44g/cm³
Use:
- methyl 2-fluororo-5-nitrobenzoate is a commonly used organic synthesis intermediate that can be used to synthesize other organic compounds.
-It has a wide range of applications in the fields of drugs, pesticides and dyes.
Method:
The preparation method of methyl 2-fluororo-5-nitrobenzoate can be carried out by the following steps:
1. First, methyl 2-fluorobenzoate is reacted with nitric acid to generate 2-fluoro-5-nitrobenzoic acid.
2. Then, the obtained 2-fluoro-5-nitrobenzoic acid is reacted with methanol in the presence of an acid catalyst to generate methyl 2-fluororo-5-nitrobenzoate.
Safety Information:
- methyl 2-fluororo-5-nitrobenzoate is an organic compound, and you need to pay attention to safety measures during operation.
-It may be irritating to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment such as gloves, safety glasses and masks when handling.
-During storage and handling, it is necessary to avoid contact with strong oxidants such as oxidants to avoid the risk of fire or explosion.
-Read and follow the relevant safety guidelines and operating procedures before use.
Last Update：2024-04-09 21:01:54
